Childhood trauma and dissociative experiences in patients with schizophrenia, major depression disorders and normal group
Journal of Research in Psychopathology
مقاله 5 ، دوره 6، شماره 4 - شماره پیاپی 22 ، 2025، صفحه 31-39 اصل مقاله (685.43 K )
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22098/jrp.2025.16956.1294
نویسندگان
ali mohammadzadeh* 1 ؛ faezeh sharifi 1 ؛ zahra heyran sangestani 2 ؛ somayeh gholizadeh 1
1 Department of Psychology, Payame Noor University, Tehran, Iran
2 Department of Clinical Psychology, Islamic Azad University of Tabriz, Tabriz, Iran
چکیده
Childhood traumatic and dissociative experiences play a crucial role in psychological disorders, with schizophrenia and major depressive disorder being two serious conditions that require examination of various etiological and maintaining factors. In Iran, the lack of sufficient research evidence comparing childhood traumatic and dissociative experiences between these two disorders is a significant research gap, which this study aims to address. The population consisted of patients with major depressive disorders and schizophrenia who visited Razi Hospital and psychiatric clinics in Tabriz from 2020 to 2023. Among them, 68 patients with major depressive disorders and 68 patients with schizophrenia were selected and tested on a voluntary basis. A non-patient group of 68 individuals was selected based on matched characteristics from students and other citizens of Tabriz. Participants responded to scales measuring dissociative symptoms and childhood trauma. The data was analyzed using multivariate analysis of variance. The results showed that patients with major depressive disorder and schizophrenia scored higher on childhood traumatic and dissociative experiences compared to the control group. Additionally, when comparing the two patient groups, patients with major depressive disorder scored higher on childhood traumatic experiences, while patients with schizophrenia scored higher on dissociative experiences. This study revealed that patients with major depressive disorder scored higher on childhood traumatic experiences compared to patients with schizophrenia, while schizophrenia patients exhibited higher scores on dissociative symptom.
کلیدواژهها
Childhood trauma ؛ Dissociation ؛ Dissociative experiences ؛ Major depression ؛ Schizophrenia
مراجع
Alphs, L., Baker, P., Brown, B., Fu, D. J., Turkoz, I., & Nuechterlein, K. H. (2022). Evaluation of major treatment failure in patients with recent-onset schizophrenia or schizophreniform disorder: A post hoc analysis from the Disease Recovery Evaluation and Modification (DREaM) study. Schizophrenia Research , 248 , 58-63. doi:10.1016/j.schres.2022.02.019
American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders: DSM-5-TR . Washington, DC: American psychiatric association. doi:10.1176/appi.books.9780890425787
Amrollahi, S., Moradi, A., & Hassani, J. (2016). The Effectiveness of Memory Specificity Training on Cognitive and Dissociative Experiences in Patients with Post-Traumatic Stress Disorder. Cognitive Psychology , 4(3), 31-40. (In Persian) dor:20.1001.1.23455780.1395.4.3.5.6
Baldessarini, R. J., Miola, A., & Tondo, L. (2025). Affective temperaments: Effects on treatment response for major depression. Asian Journal of Psychiatry , 103 , 104335. doi:10.1016/j.ajp.2024.104335
Basharpoor, S, Shafiei, M., Atadokht ,A., Narimani, M. (2015). The Role of Experiential Avoidance and Mindfulness in Predicting the Symptoms of Stress Disorder after Exposure to Trauma in Traumatized People Supported by Emdad Committee and Bonyade Shahid Organization of Gilan Gharb in the First Half of 2014. JRUMS, 14 (5), 405-416. Doi: 20.1001.1.17353165.1394.14.5.2.8
Begemann, M. J., Schutte, M. J., Van Dellen, E., Abramovic, L., Boks, M. P., Van Haren, N. E., ... & Sommer, I. E. (2023). Childhood trauma is associated with reduced frontal gray matter volume: a large transdiagnostic structural MRI study. Psychological medicine , 53 (3), 741-749. doi:10.1017/S0033291721002087
Bernstein, E. M., & Putnam,F. W. (1986). Development, reliability, and validity of a dissociation scale. The Journal of Nervous and Mental Disease, 174(12), 727–735. doi:10.1097/00005053-198612000-00004
Bernstein, D. P., Stein, J. A., Newcomb, M. D., Walker, E., Pogge, D., Ahluvalia, T., ...& Zule, W. (2003). Development and validation of a brief screening version of the Childhood Trauma Questionnaire. Child abuse & neglect , 27 (2), 169-190. doi:10.1016/S0145-2134(02)00541-0
Bruce, A. S., Ray, W. J., & Carlson, R. A. (2007). Understanding cognitive failures: What’s dissociation got to do with it?. The American Journal of Psychology , 120 (4), 553-563. doi:10.2307/20445425
Butler, L. D. (2006). Normative dissociation. Psychiatric Clinics , 29 (1), 45-62. doi:10.1016/j.psc.2005.10.004
Calciu, C., Macpherson, R., Rees, K. J., Chen, S. Y., Ruxton, S., White, R., ...& Soponaru, C. (2025). Exploring the relationship between dissociative experiences and recovery in psychosis: cross-sectional study. British Journal of Psychlogical Bulletin , 1-10. doi:10.1192/bjb.2024.113
Carlson, E. B., & Putnam, F. W. (1993). An update on the dissociative experiences scale. Dissociation: progress in the dissociative disorders , 6(1), 16–27. doi:10.13110/dissociation.6.1.0016
Chiu, C. D., Li, D. J., Hsieh, Y. C., Chou, L. S., Au, J. S., Chen, Y. L., & Lin, C. H. (2024). Linking childhood trauma and dissociation to psychotic symptoms in major depressive disorder, bipolar disorders, and schizophrenia: A transdiagnostic examination using patient and clinician ratings. Psychological trauma: theory, research, practice, and policy , 16 (S1), S242. doi:10.1037/tra0001584
De Vos, C., Thompson, A., Amminger, P., Bendall, S., de Haan, L., Hartmann, J., ...& Nelson, B. (2019). The relationship between childhood trauma and clinical characteristics in ultra-high risk for psychosis youth. Psychosis , 11 (1), 28-41. doi:10.1080/17522439.2019.1582686
Du, Y., Liu, J., Lin, R., Chattun, M. R., Gong, W., Hua, L., ...& Yao, Z. (2024). The mediating role of family functioning between childhood trauma and depression severity in major depressive disorder and bipolar disorder. Journal of Affective Disorders , 365 , 443-450. doi:10.1016/j.jad.2024.08.155
Ebrahimi, H., Dezhkam, M., & Seghat-ol-eslam, T. (2013). Childhood Trauma and Suicidal Attempts in Adulthood. Iranian Journal of Psychiatry and Clinical Psychology , 19(4), 275-282. (In Persian) https://ijpcp.iums.ac.ir/article-1-2090-fa.html
Fung, H. W., Chien, W. T., Lam, S. K. K., & Ross, C. A. (2022). Prevalence and correlates of dissociative symptoms among people with depression. Journal of psychiatric research , 154 , 132-138. doi:10.1016/j.jpsychires.2022.07.054
Fung, H. W., & Cheung, C. T. Y. (2024). The bidirectional relationship between depression and dissociation: A longitudinal investigation. Asian Journal of Psychiatry , 94 , 103940. doi:10.1016/j.ajp.2024.103940
Fung, H. W., Ho, G. W. K., Lam, S. K. K., Chau, A. K. C., Şar, V., Ross, C. A., ... & Wong, J. Y. H. (2025). The co-occurrence of depression and dissociation: The relevance of childhood trauma. Journal of Psychiatric Research, 183 , 157–163. doi:10.1016/j.jpsychires.2025.02.026
Garrivet, J., Maruani, J., Mauries, S., Trzepizur, W., Lejoyeux, M., Gohier, B., & Geoffroy, P. A. (2025). Increased sleep duration and emotional regulation in patients with major depressive episodes. Journal of Psychiatric Research , 184 , 210-215. doi:10.1016/j.jpsychires.2025.02.048
Giannopoulou, I., Georgiades, S., Stefanou, M. I., Spandidos, D. A., & Rizos, E. (2023). Links between trauma and psychosis. Experimental and Therapeutic Medicine , 26 (2), 386. doi:10.3892/etm.2023.12085
Hassan, A. N., Stuart, E. A., De Luca, V., (2016). Childhood maltreatment increases the risk of suicide attempt in schizophrenia. Schizophria Research , 176(2-3), 572-577. doi:10.1016/j.schres.2016.05.012
Holowka, D. W., King, S., Saheb, D., Pukall, M., & Brunet, A. (2003). Childhood abuse and dissociative symptoms in adult schizophrenia. Schizophrenia research , 60 (1), 87-90. doi:10.1016/s0920-9964(02)00296-7
Holtzman, C. W., Trotman, H. D., Goulding, S. M., Ryan, A. T., Macdonald, A. N., Shapiro, D. I., ... & Walker, E. F. (2013). Stress and neurodevelopmental processes in the emergence of psychosis. Neuroscience , 249 , 172-191. doi:10.1016/j.neuroscience.2012.12.017
Isvoranu, A. M., van Borkulo, C. D., Boyette, L. L., Wigman, J. T., Vinkers, C. H., Borsboom, D., et al., (2017). A network approach to psychosis: pathways between childhood trauma and psychotic symptoms. SchizophreniaBulletin . 43(1), 187-196. doi:10.1093/schbul/sbw055
Levin, Y., Bachem, R., Brafman, D., & Ben-Ezra, M. (2024). The association between dissociative symptoms and schizophrenia-related negative symptoms: A transdiagnostic approach. Journal of Psychiatric Research , 169 , 81-83. doi:10.1016/j.jpsychires.2023.11.016
Longden, E., Branitsky, A., Moskowitz, A., Berry, K., Bucci, S., & Varese, F. (2020). The relationship between dissociation and symptoms of psychosis: a meta-analysis. Schizophrenia bulletin , 46 (5), 1104-1113. doi:10.1093/schbul/sbaa037
Lorzangeneh, S., & Esazadegan, A. (2022). The role of early maladaptive schema domains and childhood trauma in predicting cognitive distortions. Journal of research in psychopathology , 3 (8), 1-8. doi:10.22098/JRP.2022.10098.1049
Lynn, S. J., Maxwell, R., Merckelbach, H., Lilienfeld, S. O., van Heugten-van der Kloet, D., & Miskovic, V. (2019). Dissociation and its disorders: Competing models, future directions, and a way forward. Clinical psychology review , 73 , 101755. doi:10.1016/j.cpr.2019.101755
Lyssenko, L., Schmahl, C., Bockhacker, L., Vonderlin, R., Bohus, M., & Kleindienst, N. (2018). Dissociation in psychiatric disorders: a meta-analysis of studies using the dissociative experiences scale. American Journal of Psychiatry , 175 (1), 37-46. doi:10.1176/appi.ajp.2017.17010025
Magruder, K. M., McLaughlin, K. A., & Elmore Borbon, D. L. (2017). Trauma is a public health issue. European journal of psychotraumatology , 8 (1), 1375338. doi:10.1080/20008198.2017.1375338
Misiak, B., Krefft, M., Bielawski, T., Moustafa, A. A., Sąsiadek, M. M., & Frydecka, D. (2017). Toward a unified theory of childhood trauma and psychosis: a comprehensive review of epidemiological, clinical, neuropsychological and biological findings. Neuroscience & Biobehavioral Reviews , 75 , 393-406. doi:10.1016/j.neubiorev.2017.02.015
Michel, C., Kindler, J., & Kaess, M. (2022). Traumatic experiences in childhood and the development of psychosis spectrum disorders. European child & adolescent psychiatry , 31 (2), 211-213. doi:10.1007/s00787-021-01938-9
Mohammadzadeh, A., Daneshyar Asl, T., & Farsad Khatibi, H. (2024). Validation of the short Oxford-Liverpool Inventory of Feelings and Experiences (SO-LIFE) on an Iranian sample. Journal of Research in Psychopathology , 5 (17), 33-41. doi:10.22098/JRP.2024.14650.1224
Mørkved, N., Winje, D., Dovran, A., Arefjord, K., Johnsen, E., Kroken, R.A., et al., (2018). Childhood trauma in schizophrenia spectrum disorders as compared to substance abuse disorders. Psychiatry Research , 261, 481-487. doi:10.1016/j.psychres.2018.01.011
Popovic, D., Schmitt, A., Kaurani, L., Senner, F., Papiol, S., Malchow, B., ...& Falkai, P. (2019). Childhood trauma in schizophrenia: current findings and research perspectives. Frontiers in neuroscience , 13 , 274. doi:10.3389/fnins.2019.00274
Schiltz, H. K., Van Hecke, A. V., Putney, J. M., & Hartley, S. L. (2024). Predicting longitudinal trajectories of adaptivecouple processes in families of autistic children: Applying the Vulnerability Stress Adaptation model. Research in Autism Spectrum Disorders , 118 , 102468. doi:10.1016/j.rasd.2024.102468
Schmitt, A., Malchow, B., Hasan, A., & Falkai, P. (2014). The impact of environmental factors in severe psychiatric disorders. Frontiers in neuroscience , 8 , 19. doi:10.3389/fnins.2014.00019
Shadrina, M., Bondarenko, E. A., & Slominsky, P. A. (2018). Genetics factors in major depression disease. Frontiers in psychiatry , 9 , 334.1-18. doi:10.3389/fpsyt.2018.00334
Sheffield, J. M., Williams, L. E., Woodward, N. D., & Heckers, S. (2013). Reduced gray matter volume in psychotic disorder patients with a history of childhood sexual abuse. Schizophrenia research , 143 (1), 185-191. doi:10.1016/j.schres.2012.10.032
Steenkamp, L. R., Parrish, E. M., Chalker, S. A., Badal, V. D., Pinkham, A. E., Harvey, P. D., & Depp, C. A. (2023). Childhood trauma and real-world social experiences in psychosis. Schizophrenia research , 252 , 279-286. doi:10.1016/j.schres.2022.12.039
Şar, V. (2015). Dissociative depression is resistant to treatment-as-usual. Journal of Psychology and Clinical Psychiatry , 3 (2), 00128. Teicher, M. H., & Samson, J. A. (2013). Childhood maltreatment and psychopathology: A case for ecophenotypic variants as clinically and neurobiologically distinct subtypes. American journal of psychiatry , 170 (10), 1114-1133. doi:10.1176/appi.ajp.2013.12070957
Vancappel, A., Graux, J., & El-Hage, W. (2024). Exploring cognitive behavioral mechanisms related to dissociation among patients suffering from schizophrenia: A pilot study. European Journal of Trauma & Dissociation , 8 (4), 100469. doi:10.1016/j.ejtd.2024.100469
Van Os, J., & Linscott, R. J. (2012). Introduction: the extended psychosis phenotype—relationship with schizophrenia and with ultrahigh risk status forpsychosis. Schizophrenia bulletin , 38 (2), 227-230. doi:10.1093/schbul/sbr188
Van Winkel, R., Stefanis, N. C., & Myin-Germeys, I. (2008). Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction. Schizophrenia bulletin , 34 (6), 1095-1105. doi:10.1093/schbul/sbn101
Ware, K., Misiak, B., Hamza, E. A., Nalla, S., & Moustafa, A. A. (2024). The Impact of Childhood Trauma on the Negative Symptoms of Schizophrenia. The Journal of Nervous and Mental Disease , 212 (9), 460-470. doi:10.1097/NMD.0000000000001788
Williams-Butler, A., Howard, T., Anthony, W. L., & Duron, J. (2023). Adverse Childhood Experiences, sexual debut and substance use among Black justice-involved youth: The imperative of trauma-informed sexuality education. Children and Youth Services Review , 147 , 106-47. doi:10.1016/j.childyouth.2023.106847
Xie, P., Wu, K., Zheng, Y., Guo, Y., Yang, Y., He, J., ...& Peng, H. (2018). Prevalence of childhood trauma and correlations between childhood trauma, suicidal ideation, and social support in patients with depression, bipolar disorder, and schizophrenia in southern China. Journal of affective disorders , 228 , 41-48. doi:10.1016/j.jad.2017.11.011
Zhang, L., Zhao, N., Zhu, M., Tang, M., Liu, W., &Hong, W. (2023). Adverse childhood experiences in patients with schizophrenia: related factors and clinical implications. Frontiers in psychiatry , 14 , 1247063. doi:10.3389/fpsyt.2023.1247063
آمار
تعداد مشاهده مقاله: 96
تعداد دریافت فایل اصل مقاله: 46